So, this cycle didn't start out much better. Only 3 follicles seen on the initial u/s, but we charged ahead anyways.
Not much has happened and the doc's wanted to cancel us yesterday. Estrogen has not been rising as much as it should. But, I feel why bother cancelling? What's cancelling going to get me. It's certainly not going to get me pregnant!
So, there were 2 good follicles today and 3-4 little ones. I have good
insurance and meds are only a $40 co pay. So, I talked the doc into
continuing on at a lower dose to try to get those 2 to grow and either
doing timed intercourse or an IUI. None of this makes any sense. We
never had a problem getting pregnant. The longest amount of time to conceive was 4 months!
I'm trying to figure out what went so wrong and there were only 2 things
that changed from testing to cycling. That was the addition of
dexamethasone and the birth control pill. I'm starting to suspect the
dex even though the doc says it can't be the problem. If DHEA is so
important to older women (and lots of studies say it is), dex is the
Dexamethasone causes DHEA to fall. I asked the doc today about DHEA and
he felt it doesn't really do anything, but if I want to try it go
ahead. Well, I know the studies show it does do alot for women with DOR.
Here's a list of the studies in case anybody's wondering: http://www.centerforhumanreprod.com/dhea.html
So maybe after a few months and the dex gets out of my system... After
looking that up, the half life of dex is only 36-54 hours, so it should
be all out of my system. The more depressing theory is that since DHEA
seems to work at improving the follicular environment, the dex may have
damaged the follicular environment. Since folliculogenesis takes months
it may be a long time before the follicular environment has recovered
from the assault. I'll know I'm right if my AFC recovers over the next
So, doc also ordered an AMH test. That's fine I've never had one. If the
AMH comes back low, we'll know it's DOR. If it comes back ok, the doc's
other theory is that some women's bodies just don't respond to
exogenous FSH. So, all the Follistim in the world wouldn't have that
much effect on me. In that case, the only other answer is to use my
body's own hormones through a Lupron flare protocol or clomid.
So much to think about...